Cialis is a modern, long-lasting remedy for treating erectile dysfunction. There are many types of Cialis for sale in the pharmaceutical market. Reading this article, you will understand about the different types of the medication.
Cialis for Sale – Genuine Version
Cialis is a very effective medication designed to cure erection problems, i.e. the inability of a man to get or maintain the penile erection necessary for normal, sexual penetration. The medication is included in the group of medical drugs for curing erectile problems (the so-called PDE5 inhibitors) and is manufactured by Eli Lilly (the U.S. pharmaceutical giant). The main, active agent of this medication is tadalafil. It is actively used around the world and as an effective remedy for elimination of erectile dysfunction.
The medication has a unique principle of action. It works as a selective suppressor of the PDE5 enzyme found in the body, especially inside the penile organ. When strong, sexual excitement leads to the release of nitric oxide (NO) inside the penis, the suppressing of PDE5 by this agent causes an increase in cGMP quantities in the penis, namely in the corpora cavernosa. Thanks to this action, the drug contributes to the relaxation of penile muscles and arteries. Therefore, the flow of blood to the tissues of the penile organ increases. These factors lead to the occurrence of an erection.
It should be noted that the medication doesn’t provide the effect if there is no adequate natural sex stimulation. Cialis 5mg only improves the natural triggers of erection occurring. In addition, it enhances an erection and allows a man to have a successful, sexual penetration (after sex, the penis will naturally return to the non-erected condition). You can test this effect after purchasing the medication or getting a Cialis free trial.
When does Cialis start its action and how long does it last? The effect of the medication is manifested as early as 15-20 min after administration (if natural, sexual arousal is present). It provides ongoing action during the fantastic period (36 hours after administeration). As a result, a male can attempt to have sexual intercourse at any moment during 1.5 days. However, in some patients, the medication acts during the shorter period. This medication doesn’t cause a significant change in arterial pressure in healthy males compared with a placebo.
The only indication for the use of Cialis pills is erectile dysfunction. This condition should be diagnosed by a health care professional. Self-treatment with Cialis can be dangerous for one’s health. The medication has the following contraindications:
1) age under 18;
2) hypersensitivity to the key ingredient (tadalafil) or to any other components contained in the tablets;
3) treatment with any drugs that contain organic nitrates (combination of Cialis and nitrates can be very dangerous for one’s health!).
The genuine version of the medication is available in several dosages: 2.5mg, 5mg, 10mg, and 20mg. It comes in the form of light-yellow tablets that look like almonds.
History of Genuine Cialis
After the approval of Pfizer’s Viagra by the U.S. Food and Drug Administration in 1998, Pfizer company actually had a monopoly on an effective and extremely popular drug, which, during the first year of sales, brought Pfizer a billion dollars. This situation (very favorable for Pfizer) lasted for five years, until 2003, when two new drugs for the treatment and prevention of impotence appeared on the market. They were Cialis (tadalafil) and Levitra (vardenafil).
What is the history of Cialis? In 1993, the pharmaceutical corporation Icos (trademark ICOS) began to study an inhibitor of phosphodiesterase type 5 (PDE5 inhibitor). This substance was called IC351. Nowadays, practically all the most-effective drugs for the treatment and prevention of erectile dysfunction in men are produced on the basis of PDE-5 inhibitors.
In the 20th century, the situation was completely different, because it’s enough to remember that the invention of the first drug on the basis of the PDE-5 inhibitor, in general, was only a happy accident. At that time, erectile dysfunction was cured with the help of penile injections and other unpleasant methods.
Although Icos began operating in 1990, and the first patent for the IC351 inhibitor was received by it in 1994, it remains unclear whether this patent was granted earlier or later than when Pfizer received a patent for Viagra.
However, in 1995, Icos Corporation began the first phase of clinical trials of the drug. Two years later, the second stage began, during which the drug was tested on patients with various deteriorations of sexual function. These studies lasted two years, and in 1998, to create Tadalafil, Icos Corporation had teamed up with Eli Lilly (a large, American pharmaceutical corporation). As a result, two years later, Lilly and Icos made a statement at the 97th Congress of the American Urological Association in Florida that the Cialis medication with the active substance Tadalafil remained effective for 36 hours. This was a real revolution in the world of medicine (Viagra works only 4-6 hours).
Cialis for Sale Online – Generic Versions
The medicament is still patented in some countries, such as the USA. However, in most countries, the patent for Cialis has expired. Therefore, generic drugmakers receive the right to produce generic copies of the medication.
Many people don’t know what generics are. They believe that generics are counterfeited versions of the most effective and popular medicines. However, this opinion isn’t true. Even the World Health Organization supports the manufacturing of generics (production of exact copies of original drugs).
The production of copies of medicines at the highest level (the level of production of the original) can be done not by all pharmaceutical companies. Today India and China are leaders in the production of generics. India has had a powerful pharmaceutical industry for many decades.
The chemical formula of many hundreds of Indian generics has absolutely no difference from the original meds. The key difference lies only in price. Low cost is a big advantage for generics. Having the same qualities as originals, generics can be 10-20 times cheaper. Even if in some cases their price can be quite high, it is still at least 20-30% cheaper than the original, medical product.
The generic company does not spend a lot of money on the development of medicines and clinical trials. It just finds the best way of resynthesizing the original, chemical formula. Based on this, the company produces medication in huge quantities with minimal, production expenses.
There are many Indian generics on the pharmaceutical market. Among them are Tadaga, Erectafil, Tadalafil, Vidalista (chewable tabs), etc. These drugs aren’t available in the U.S., but you can buy them in Canada.
40mg Cialis – Is It Safe?
Often you can see the generics of Cialis on sale that contain a very high dosage of the active substance. Such dosages can reach 40mg, 80mg, 100mg and more. Manufacturers of medicines state that an increased dosage provides higher efficacy. However, this is not quite true. Efficacy may slightly increase, but together with it, the risk of side effects increases significantly! This can lead to a severe overdose manifested in the rapid, lowering of blood pressure, headaches, redness of the face, and other, extremely unpleasant phenomena. Remember, the maximal possible dosage of the medicament is 20mg.
Cialis for Sale – Liquid Version
Liquid Cialis is a unique version of the drug intended for men who hate swallowing pills. It should be taken 15-20 minutes before sexual intercourse. Due to its liquid form, the drug is absorbed more quickly than tablets. Therefore, a man can experience the desired effect in just 15 minutes after consuming the liquid. It is supplied in small bottles that should be stored in a dark place at room temperature.
Cialis for Sale – Natural (Herbal) Remedies
Many drugstores selling different meds for sale online offer natural (herbal) versions of Cialis. They position this product as a natural alternative to “chemical” medications. Some people are interested in buying such a product for several reasons. First, they cannot buy the original version of Cialis because of its high price. Secondly, adherents of a healthy lifestyle try to choose only natural products.
However, unfortunately, the effectiveness of herbal remedies has not been proven. Moreover, they can be hazardous to one’s health. Some additives contain harmful chemical compounds and active agents from the group of PDE5 inhibitors (to simulate the effect of original medicines). If you plan to take such supplements, it is best done under the supervision of an expert who specializes in non-traditional medicine. Therefore, real Cialis cannot be herbal. If you want to cure ED, use the original drug or its legal generics.